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The stable lines stand for the modified odds ratios, as well as shaded parts symbolize the ninety five% CIs. In restricted cubic splines analysis, knots were being placed within the tenth, 50th, and 90th percentiles of ADHD medication use.
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Discussion This substantial, nested case-Handle study uncovered an elevated risk of incident CVD linked to lengthy-expression ADHD medication use, and the chance greater with raising period of ADHD medication use. This Affiliation was statistically significant the two for children and youth and for adults, as well as for women and males.
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aControls ended up derived from your similar foundation cohort as the cases; thus, a case having a later on day of CVD diagnosis could potentially function a control for an additional case from the study.
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